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New paper from Dr. Wen Gu on the impact of L-2-hydroxyglutarate deficiency on neural stem cell function and neuronal differentiation. Interesting connection between an IEM and chronic oncogene activation. Thanks to Dr. Bushra Afroze and her patients for participating. www.jci.org/articles/vie...
www.jci.org
JCI - L-2-hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression
2mo
DeBerardinis Lab at UT Southwestern Medical Center