All about improving therapeutic outcomes to TMS and neurofeedback using replicated and clinically actionable biomarkers.
But why use 8mg+8mg in prospective Ph3 study (instead of 8+12mg)? Use of 4mg as a control also sounds risky, might lack 'dose-response' effects.
Looking forward presenting tomorrow, will bridge the gap between biofeedback and TMS-induced Heart-Brain Coupling.
Online meeting, so accesible from anywhere...
See you there!
aapb.starchapter.com/meetinginfo....
Look forward to presenting @UCLA on alpha frequency and heart-brain coupling as biomarkers for personalized TMS.
Impressive results by AtaiBeckley re BPL-003: 76% remission after just 2 doses (8mg+12mg) after 2 mo. in Ph2B. Higher than other interventional psychiatry tx such as accelerated TMS, requiring less time.
Look forward presenting a keynote and workshop at ISNR conference in Las Vegas in August. Will focus on Heart-Brain Coupling and QEEG-based Stratified Psychiatry in ADHD and Depression.
See you there?
web.cvent.com/event/cdfcfc...
To put this into perspective, here all reponse/remission rates for current treatments in MDD and TRD from largest open-label trials incl. STAR*D, iSPOT-D, Blumberger et al. etc. Normally 30-40% remission rate in TRD.
See here for refs: www.nature.com/articles/s44...
Even taking more specific TRD treatments e.g. SAINT (50% remission); our own TMS+psychotherapy data (56% remission), a 76% remission rate is high.
SAINT Replication: onlinelibrary.wiley.com/doi/10.1002/...
TMS+Psychotherapy: www.brainstimjrnl.com/article/S193...
