#rustbio 4.0 has been released. It harmonizes the error handling, improves the API, makes gap-open/extend behavior in pairwise alignment more intuitive and in-line with the literature, improves GFF parsing, and allows incremental building of the rank-select datastructure. github.com/rust-bio/rus...
Excited to share our review relating to the giant extrachromosomal elements (ECEs)
We cover: why long-read metagenomics enables their discovery, genomic comparisons across recently characterized examples, and limitations of current classification tools.
www.cell.com/trends/genet...
4.0.0 (2026-06-12)
⚠ BREAKING CHANGES
Replace anyhow with typed thiserror errors (#674)
Change Phase conversion methods to use TryFrom for better error handling (#625)
for pairwise alignment, only...
github.com
🧬 New preprint! We clustered 5.6 million bacterial genomes into genomically cohesive units (GCUs) 500× faster than existing tools. (In just 14 hours, 16.5 GB RAM using 48 CPUs). 🦠🐙Meet gemsparcl 💎✨!
www.biorxiv.org/content/10.6...
New blog post!
I analyse the new [email protected] basecalling model from @nanoporetech.com and discuss the conspicuous lack of a new sup model:
rrwick.github.io/2026/06/11/d...
Minibwa is a hybrid of bwa-mem and minimap2 and the successor of bwa-mem for short-read mapping. ~4X/2.5X as fast as bwa-mem/bwa-mem2 for WGS reads at comparable accuracy. Native support of directional bisulfite-seq. Applicable to long reads. Preprint at arxiv.org/abs/2606.15357
Excited to have Alex Crits Christoph @acritschristoph.bsky.social join the lab today as a staff scientist!
I had a hunch it was good time to find an experienced computational microbiologist to join the lab, but still feel very lucky to have him joining us. Looking forward to cool science!
