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Prof @ Harvard University, Broad Institute, and Wyss Institute. Synthetic & systems biology. Trying to understand the living world by engineering a synthetic one. Lab website: bu.edu/khalillab
Mo Khalil









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🌱 NEW PREPRINT & SPECIAL day! We unveil an advance for plant science, engineering, and synbio in first (of many) Khalil <> Gehring collabs, led by the one-and-only @willshaw.bsky.social. Thread below on principles + design of a new, single-integrating T-DNA vector for precision plant xformation! 👇
What an honor to receive the Kuwait Prize! A testament to the remarkable achievements and hard work of #Khalil-Lab members past and present. It’s always an honor to be recognized as a scientist, and especially meaningful to celebrate my background as a Palestinian-Jordanian 🙏 tinyurl.com/2jvrjszb
And here is another direct link to the preprint. Enjoy! www.biorxiv.org/content/10.6...
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Busy week for the Khalil lab getting ready of our big move next week! P.s. Graveyard of Oligos 🧬 from our prolific former postdoc @willshaw.bsky.social
Calling all Scientists! Research Administrators! Deans! Fans of Science! No one is coming to save us. Here is your assignment. I have written a step by step, easy to understand "how-to" document to help you comment on the proposed OMB rule. elizabethginexi.substack.com/p/what-we-ne...
Interrupting the regular (science) broadcast to brag about my wife and Hisel Flynn Architects on having their beautiful work featured in the @bostonglobe.com! 🏠😍 www.bostonglobe.com/2026/03/26/m...
🚨 An exciting frontier is bringing synthetic biology to MULTIcellular systems. To effectively engineer them, we need design principles. What are the benefits of group formation? What are the costs? See our new preprint led by @heidiklumpe.bsky.social to learn more!👇 www.biorxiv.org/content/10.6...
Startups are providing tantalizing glimpses of AI-assisted antibody discovery and claiming game-changing potential, even as new models remain hidden and industry awaits full disclosure and benchmarking www.nature.com/articles/s41... [🔓read free with login]
5 days left now to apply for the postdoc opportunity in my lab at Imperial in London 🇬🇧 - there’s a chance that we can hire 2 people into the team on this synthetic biology and materials theme. Application link is here - www.imperial.ac.uk/jobs/search-...
Unstructured transcription factor interactions enable emergent specificity | @science.org www.science.org/doi/10.1126/...
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What OMB’s Proposed Federal Financial Assistance Rule Means in Practice
elizabethginexi.substack.com
Mo Khalil
What We Need to do NEXT: OMB’s Proposed Federal Financial Assistance Rule (OMB 2026-10817)
How intrinsically disordered regions (IDRs) influence chromatin binding and nuclear organization of transcription factors (TFs) remains unclear. We employed proximity-assisted photoactivation (PAPA), ...
www.science.org
Unstructured transcription factor interactions enable emergent specificity
Mo Khalil
Mo Khalil
Mo Khalil
Mo Khalil
Mo Khalil