Novel compact CRISPR systems unlock easier delivery and more applications... epigenome editing anyone 👀
Very happy to be involved in work to rationally engineer enhanced Cme2 - an ultra-high fidelity & compact Cas, delivered in vivo in a single AAV (with gRNA)
www.biorxiv.org/content/10.6...
www.biorxiv.org
The development of compact and efficient CRISPR-Cas systems is crucial for biomedical and therapeutic genome editing, particularly in vivo applications based on viral delivery. Here, we performed a co...
