Congrats (again) to Julia and Abby for their collaborative effort asking when and why cells use the TCA cycle. TLDR; it's not just about ATP or making nutrients-- the TCA cycle is also important to remove nutrients!
Lydia Finley
One more thing- here, together with amazing human being, friend & stellar physician scientist Abby Xie, we identify a new function of the TCA cycle, which is citrate clearance, now online at @cellpress.bsky.social: www.cell.com/cell/fulltex...
Beyond its traditional role in supporting bioenergetic and biosynthetic demands, the
canonical TCA cycle is also essential for nutrient clearance. When pyruvate oxidation
and citrate production increa...
