Ever wondered how gut microbes control immune responses at extra-intestinal locations?
Here #theonlylabever reports how a gut protozoan commensal shapes pulmonary immunity to exacerbate asthma and limit the dissemination of mycobacteria.
@cellpress.bsky.social ⬇️(1/x)
www.cell.com/cell/fulltex...
A HUGE shout out to PhD student, @rsjpalmer.bsky.social who lead this work (imaginatively called the Epic Lung Phenotyping Project) and flow gurus @katepilki.bsky.social and Kathryn Hally whose expertise was invaluable in getting the most high quality data possible.
Kudos to Kit Moloney-Geany who generated the beautiful TLS images that brought the paper together! 🔬
Thanks to the rest of the team @malaghan.bsky.social and to Andrew Lim and the Cytek team for all their help and support 🙏
@kerryhilligan.bsky.social et al @niaidnews.bsky.social review the evidence that both the mycobacterial-specific & off-target nonspecific effects of BCG immunization require the interplay of innate & adaptive responses, the elucidation of which could improve #TB vaccines rupress.org/jem/article/...
Congratulations to @kerryhilligan.bsky.social for her Doherty Lectureship for her most excellent body of work studying tissue immunity to infections. #ASI2025 #PerthASI
Our @immunolcellbiol.bsky.social "Highlights of 2024: Germinal Centers" is now out. Led by Theresa Pankhurst, we discuss some (there's never enough space for all!) neat germinal centre papers that were published in 2024, and whose findings are moving the field forward. doi.org/10.1111/imcb...
Now up in the Thursday Plenary @kerryhilligan.bsky.social the #ASI2025 the Peter Doherty medal recipient, celebrating research excellence by ECRs
Calling all lung immunology enthusiasts 🫁
I’m excited to share this project where we designed and optimised a spectral cytometry platform to study immune responses in the mouse lung at steady-state and during viral infection. We hope this will be a useful resource for the field!
Link below 👇