Primer design for 3' end of polyadenylated transcripts for targeted RNA seq, in bulk, single-cell, or spatial mode. New from OncoRNALab at @crighent.bsky.social
Jo Vandesompele
🧪 Recently published in Bioinformatics Advances: "Peakprime: A peak-guided primer design pipeline for target enrichment in 3′-end RNA-seq"
Access the article: https://doi.org/10.1093/bioadv/vbag080
Authors include: @jvdesomp.bsky.social
Bioinformatics Advances
Phage quantification by Stefan Vermeulen at #EUDIP2025
Marvin Heyer on 260K 3.7 pL partitions- new dPCR format at #EUDIP2025
#EUDIP2025 kicks off in Ghent! All about digital PCR #dPCR digpcr.ugent.be/EUDIP2025/
Blood (literally and figuratively), sweat, and tears... rejection after 3 rounds of revisions by another journal, but now out. We are proud of this new type of biomarker identification concept - applied here on cell-free RNA from cancer patients @amorlion.bsky.social
www.nature.com/articles/s43...
The model of harmonizing general and domain-specific guidelines provides a scalable blueprint for improving reproducibility across complex biomarker development workflows in molecular diagnostics. The case for EV and qPCR www.oaepublish.com/articles/evc...
Jo Vandesompele
“I have 9 qPCR instruments” Stephen Bustin at #dPCR #EUDIP2025 meeting in Ghent!
Are you also a desperate cell-free RNA researcher? It’s not always a grim story. Philippe Decruyenaere is defending his excellent PhD thesis on extracellular RNA in non-Hodgkin lymphoma. @crighent.bsky.social
Jo Vandesompele
Morlion et al. analyze cell-free RNA in blood plasma from people with and without cancer to identify cancer-specific patterns. Individual patients exhibit unique changes in cell-free RNA, and the numb...
www.nature.com
Extracellular vesicles (EVs) have significant potential as therapeutic agents and as sources of diagnostic, predictive, and prognostic nucleic acid biomarkers. However, variability in EV workflows and...
Still possible to follow online. #EUDIP2025 All about digital PCR #dPCR digpcr.ugent.be/EUDIP2025/ great talks by Allen Chan, Noemi Castellucci, Wim Trypsteen.
Jo Vandesompele
Jo Vandesompele
Jo Vandesompele
The spatial team at OncoRNALab @ds-ugent.bsky.social posted a benchmarking preprint on DNA barcode decoding strategies www.researchsquare.com/article/rs-8... @brechtsoulliaert.bsky.social
Jo Vandesompele
Jo Vandesompele
Jo Vandesompele
Background: DNA barcoding enables multiplexed identification of biomolecules in pooled sequencing experiments, with broad applications including spatial transcriptomics. Photolithographic synthesis of...
