A big step forward in Photopharmacology, just published in Nature Medicine:
nature.com/articles/s41...
A compound we conceptualized in 2008 (PMCID: PMC4040390) and synthesized in 2010 (PMCID: PMC3401033) proves effective in human vision restoration.
A first-in-human phase 1 trial shows that intravitreal photoswitch therapy can be administered safely in advanced retinitis pigmentosa, with exploratory signals compatible with light responsiveness fo...