Excited to share our study on the Efficacy and Safety of Psilocybin in Treatment-Resistant Depression (EPISODE) - now published in @jamapsychiatry.com
A negative effect on primary outcome, but evidence for a relevant antidepressant effect of 25 mg psilocybin with psychotherapy in TRD.
Lea Mertens
Functional unblinding and expectation may confound efficacy signals in #Psilocybin trials for #Depression, making it difficult to isolate therapeutic effects of psychedelic experiences from placebo and expectancy responses.
ja.ma/4sbCm4u
