Fantastic work led by my brilliant colleague George! Honoured to have contributed to this body of work on Nucleophosmin’s role in tumour initiation.
Nadia Nasreddin
🆕Paper in @natgenet.nature.com from Georgios Kanellos in Owen Sansom's lab: Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation www.nature.com/articles/s41...
Npm1 promotes tumor formation via attenuating the integrated stress response and p53 activation in mouse WNT-driven intestinal and liver tumorigenesis.
