New preprint 🧫🧬
Spatial transcriptomics (~550,000 cells, 2,432 patient-derived organoids): we map gene expression, shape, and function in space to understand cancer biology and drug response. w/ @marianna-raps.bsky.social @khomicsko.bsky.social and Maxim Norkin
www.biorxiv.org/content/10.6...
Shout out and thanks to everyone who was a part of this; one couldn’t have done it alone.
@rgottardo.bsky.social
@markrobinsonca.bsky.social
@stephaniehicks.bsky.social
@lmweber.bsky.social
and many more.
Huge congrats to Teofila, Jeremy & Antoine on the 2026 Pfizer Research Prize 👏 #PrecisionDermatolology driven by translational #DataScience at #CHUV & @unil.bsky.social. More to come with #AI & #SpatialBiology. Hats off to Michel Gilliet for this vision.
🔗 www.pfizerresearchprize.ch/awardees-202...
Raphael Gottardo
Helena Lucia Crowell
🚀 First MOSAIC consortium paper and MOSAIC Window: a rich 60-patient public (multimodal) dataset accessible via EGA.
📄 www.biorxiv.org/content/10.1...
#CancerResearch #SpatialTranscriptomics #SingleCell #PrecisionOncology #AI
cc: @owkin.bsky.social @10xgenomics.bsky.social
Big shoutout to our own Jieran Sun onesinglecell.bsky.social for leading this team effort!
🧠📍 Benchmarking clustering in spatial transcriptomics isn’t easy — but here is SACCELERATOR
Preprint: www.biorxiv.org/content/10.1...
With markrobinsonca.bsky.social, Naveed Ishaque, Ahmed Mahfouz, Brian Long
Are you interested in #Xenium panel comparisons: 5K vs targeted? Want to increase cell-type resolution with Xenium? Read our paper and check out our SPLIT method.
www.biorxiv.org/content/10.1...
Collaboration with @khomicsko.bsky.social
cc: @10xgenomics.bsky.social
#SpatialTranscriptomics
🧬 New paper out!
🔗 www.nature.com/articles/s41...
Frustrated by noisy CITE-seq data?
ADTNorm helps normalize it and introduces a staining index to assess antibody quality.
Great work by former postdoc Ye Zheng. Supported by @hipcproject.bsky.social
#CITEseq #SingleCell #ADTNorm
📄 Study published in @natcomms.nature.com and led by Laurence de Leval, @rgottardo.bsky.social @khomicsko.bsky.social & Elo Madissoon.
@unil.bsky.social #chuv @owkin.bsky.social
