Interested in Ubiquitin, Proteostasis and Signaling
PI at @unidue-zmb.bsky.social
https://www.uni-due.de/zmb/cellular-biochemistry/index.php
Alumnus of @mpibiochem.bsky.social and @mrclmb.ac.uk
Leo Kiss
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'If a control experiment fails, does that mean that the entire experiment is poorly designed and you must restart from scratch? Often, yes— but not always. I present five examples where failed control experiments triggered entirely new fields of research.'
link.springer.com/article/10.1...
Thermo Fisher now has a page up in response to our observations. They flatly deny that images were manipulated or fabricated while repeating that images were "optimized for presentation and clarity on the website", no lie, six times.
www.thermofisher.com/us/en/home/l...
EMBO Reports - When experimental controls go wrong, it does not necessarily mean your experiment is flawed. It might well be the first sign of something unexpected.
The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes:
🖌️ Dozens more images with duplications or painting
🖨️ Hundreds of blots that all share the same background (behold slideshow below)
Video
Today I'm posting a new blog about an astonishing scientific own goal. Hundreds of papers have reported using a totally wrong antibody to investigate the tumor suppressor p16. This mistake has happened because scientists have muddled the names of two proteins.
forbetterscience.com/2026/06/02/m...
Our lab is looking for a lab technician! If you share our passion for fundamental research and happy to contribute, join us!
Catalogue entries for more than 100 antibodies sold by the research services and supply company Thermo Fisher Scientific contain images that have apparently been manipulated, according to a pair of science sleuths.
go.nature.com/4wX4yej
Reese Richardson
Scientists have long worried about the reliability of commercial antibodies, and the latest findings have sparked fresh concerns.
Interested in non-proteinaceous ubiquitination, induced proximity or glycogen? Then you should have a look at our newest article, “Ubiquitination of glycogen and metabolites in cells and tissues”, just published in Nature: www.nature.com/articles/s41...
We are hiring a new Technical Assistant (M/F/D). The position will be in the Department of Molecular Machines and Signaling. More information below :
❕ Apply until: May 5
❕ www.linkedin.com/jobs/view/43...
#hiring #jobalert #TechnicalAssistant #BTA #MTA #CTA #LabJob
Open Postdoc Position - Giant E3 ligases: mysterious mechanisms & non‑protein substrates. Interested? Join us to uncover how these molecular giants tag lipids, RNAs, sugars beyond proteins, on organelles and pathogens, to defend the cell. Details & Application here www.imp.ac.at/career/open-...
Check out our latest paper on the ubiquitination of glycogen in cells and tissues! Congratulations to Marco Jochem (@marcojochem.bsky.social) and Simon Cobbold for leading this study and to collaborators @craigagoodman1.bsky.social, @pgregorevic.bsky.social, Kai Hofmann and Thomas Hermanns.
Pipettes, planning, and protein quality control – sound like your thing? 🧬 Join the @gekaragoz.bsky.social lab and help keep cutting-edge research running smoothly ➡️ tinyurl.com/mw398bzd
