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Biologist @thesainsburylab.bsky.social. Currently doing a PhD with @kamounlab.bsky.social Curious about plant immune receptors, molecular evolution, and other stuff. 🌿💻 #evoMPMI Find out more here: amiralito.github.io
AmirAli Toghani
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Our work is out now! (www.science.org/doi/10.1126/...). We discover a selective autophagy pathway that protects plants from the mess caused by RNA viruses. Intrigued? Follow the spaghetti trail for a summary of our findings🧵-->
@khongsamchia.bsky.social Extremely excited to share the first pre-print from my PhD project in the Carella lab, co-first authored with @khongsamchia.bsky.social 🎉 (Thread below ⬇️) www.biorxiv.org/content/10.6... Huge thanks to all co-authors and the #CarellaCapybaras for all the support 😊
12d
19d
www.biorxiv.org
www.science.org
RNA viruses co-opt host endomembranes to form replication complexes, often triggering cellular stress and immune responses. Here, we show that Arabidopsis thaliana activates selective autophagy to res...
Selective autophagy fine-tunes plant immunity to promote cell survival during viral infection
Elenor Kennedy
Marion Clavel
Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade 🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇
Started off as convergent observations in the lab with Mau and led to one of my favorite works so far! Gotta love molecular evolution and receptor biology 😊🧬💻 Huge effort from @maigarro.bsky.social @mpcontreras.bsky.social for pushing this together to the end. 🤘🏻
21d
Check out our updated activation-and-release model. This one image condenses over 10 years of work from many legendary @kamounlab.bsky.social members 🤯 Big shoutout to Chih-Hang, @tolgaboz.bsky.social, Lida, Aki, Selvaraj, @jmadhuprakash.bsky.social, @hsuanpai.bsky.social, Ben and many more!
Huge team effort together with the two legends @amiralito.bsky.social & Maián! Thanks to Raoul Frijters from @rijkzwaan.bsky.social for inspiration and to @kamounlab.bsky.social for the constant support. It was a pleasure to put this story together! Check it out now👇 www.biorxiv.org/content/10.6...
21d
As seen on @biorxivpreprint.bsky.social: our story on how the dreaded late blight pathogen hijacks a helper NLR pathway is now out in its final form! 🎉 Meet AVRcap1b: the two-faced effector 🧵👇 www.science.org/doi/10.1126/...
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21d
1d
Mauricio Contreras
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AmirAli Toghani
Mauricio Contreras
Mauricio Contreras
A plant pathogen effector suppresses an activated helper NLR via a host ENTH domain–containing protein, NbTOL9a.
www.science.org
A potato late blight pathogen effector interacts with ENTH-domain protein TOL9a and an activated helper NLR to suppress immunity
Mauricio Contreras
www.biorxiv.org
A conserved structural logic underlies sensor-helper NLR communication in the NRC immune receptor network https://www.biorxiv.org/content/10.64898/2026.05.18.725810v1
A conserved structural logic underlies sensor-helper NLR communication in the NRC immune receptor network https://www.biorxiv.org/content/10.64898/2026.05.18.725810v1