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bioRxiv Biochemistry









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RNA 3D Motif Dynamics Guide Assembly of the Replication Initiation Complex in Flaviviruses https://www.biorxiv.org/content/10.64898/2026.06.16.732768v1
Multi-stage physics-informed neural networks for JAK--STAT5 signaling and ultradian insulin--glucose dynamics: latent-species identifiability and suppression of parameter-induced divergence https://www.biorxiv.org/content/10.64898/2026.06.13.728660v1
A DIA-based quantitative crosslinking mass spectrometryframework for dynamic structural proteomics https://www.biorxiv.org/content/10.64898/2026.06.16.732730v1
Ubiquitin Chloromethylketone Probe Enables Activity-based, Selective Protein Profiling of E2 Ubiquitin Conjugating Enzymes https://www.biorxiv.org/content/10.64898/2026.06.16.732757v1
RNA-dependent aggregation of a common TEV protease variant alters in vitro biomolecular condensate reconstitution https://www.biorxiv.org/content/10.64898/2026.06.16.732646v1
Cryo-EM structure of human LRRC15 reveals the basis of therapeutic antibody recognition https://www.biorxiv.org/content/10.64898/2026.06.16.732218v1
SOLiD-MaP: A Photoproximity Labeling Platform for Small Molecule Binding Site Mapping on RNA https://www.biorxiv.org/content/10.64898/2026.06.16.732620v1
Q-DOAS: A Proximity Quenching Assay for Real-Time Detection of Early Protein Aggregation Events https://www.biorxiv.org/content/10.64898/2026.06.16.732424v1
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bioRxiv Biochemistry
bioRxiv Biochemistry
bioRxiv Biochemistry
bioRxiv Biochemistry
bioRxiv Biochemistry
bioRxiv Biochemistry
bioRxiv Biochemistry
bioRxiv Biochemistry
Development of binding and activity inhibition assays for the antibiotic resistance-associated protein PhoQ https://www.biorxiv.org/content/10.64898/2026.06.15.732377v1
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Chemoselective Halogenation of Premarineosin A for Next-Generation Antimalarial Development https://www.biorxiv.org/content/10.64898/2026.06.16.732709v1
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bioRxiv Biochemistry
bioRxiv Biochemistry