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Paramecium genome(s) aficionado; small RNAs, transposable elements, chromatin biology PI at Institut Jacques Monod, Paris, France









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#ESR #VeilleESR Tribune de la C3N du #CNRS signée par plus de 700 scientifiques (membres du comité national, directrices et directeurs d'unités) pour alerter une nouvelle fois sur les conséquences des coupes budgétaires c3n-cn.fr/2026/04/10/b...
✍️ The Duharcourt Lab ( @sandraduharcourt.bsky.social ) published a new article 📖 Genome biology 📃 A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium 🔗 buff.ly/Wn5OD0c ⬇️ Scientific news published by @cnrsbiologie.bsky.social
Thank you @cnrsbiologie.bsky.social for the highlight (in French) of our work www.insb.cnrs.fr/fr/cnrsinfo/...
Thank you @cnrsbiologie.bsky.social for the highlight on our recent publication!
Please join the upcoming Jacques Monod Conference on the mechanistic and evolutionary basis of programmed DNA elimination in Roscoff, France. Deadline for abstract submission extended to May 20, 2026. cjm.sb-roscoff.fr/en/conferenc...
The Jacques Monod Conference on the mechanistic and evolutionary basis of programmed DNA elimination is approaching. There are selected talk slots available. Abstract submission deadline: Tuesday, May 5, 2026.
#JobOffer 💼 Ingénieur d’étude H/F en biologie moléculaire 📍Institut Jacques Monod, @mnprioleau.bsky.social Lab 📆 1e juillet 2026 Candidatez sur le portail emploi CNRS avant le 13 mai 2026 🔗 emploi.cnrs.fr/Offres/CDD/U...
👋 Transposon lovers: registration is now open for the CSHL TE meeting! We have a 🔥 lineup of invited speakers and many slots for short talks selected upon abstract across all areas of TE biology. 🧬➰🧬 #TEsky Abstract deadline: July 10 meetings.cshl.edu/meetings.asp...
now published at BMC Biology! rdcu.be/fdITD
✍️ The @sandraduharcourt.bsky.social Lab published a new article 📖 Genome Biology 📃 A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium 🔗 link.springer.com/article/10.1...
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Une marque épigénétique qui active pour mieux réprimer
Chez les eucaryotes, la marque épigénétique H3K27me3 est classiquement associée à la répression transcriptionnelle.
www.insb.cnrs.fr
c3n-cn.fr
Coordination des instances du Comité National
Institut Jacques Monod
Alexis Verger 🧬🧫🧪
Institut Jacques Monod
cjm.sb-roscoff.fr
The mechanistic and evolutionary basis of programmed DNA elimination | CNRS - Conférences Jacques Monod (CJM)
Cedric Feschotte
Institut Jacques Monod
rdcu.be
The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of Helitrons
#ResultatScientifique🔎|Activer pour mieux réprimer ? Chez la paramécie, la transcription aide à verrouiller le génome contre les éléments mobiles🧬 ✍️ @sandraduharcourt.bsky.social 📕 Genome Biology ▶️ buff.ly/RgSZhfQ 🤝 @ijmonod.bsky.social @upcite.bsky.social @cnrs-idf-villejuif.bsky.social @cnrs.fr
#ResultatScientifique🔎| Dans une étude publiée dans BMC Biology, des scientifiques révèlent que les extrémités des chromosomes germinaux chez la paramécie sont éliminées par un mécanisme inédit. ✍️ Sandra Duharcourt & Linda Sperling buff.ly/U9pshl7
Excited to announce the upcoming Jacques Monod Conference on the mechanistic and evolutionary basis of programmed DNA elimination (Sept 21–25, 2026): cjm.sb-roscoff.fr/en/conferenc... Organized by @laurarossevo.bsky.social and myself.
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The Jacques Monod Conference on the mechanistic and evolutionary basis of programmed DNA elimination is approaching. There are selected talk slots available. Abstract submission deadline: Tuesday, May 5, 2026.
1mo
Excited to share our new preprint on BioRxiv! A collaborative effort spanning many years and several labs to uncover what the germline chromosomes of Paramecium really look like. 🔗 www.biorxiv.org/content/10.1... 1/5
Our latest publication is now out at Genome Biology! link.springer.com/article/10.1... We uncover a unique association between a H3K27me3 reader complex and active transcription. A thread with our key findings: (1/8) #TEsky #Polycomb #transcription #smallRNAs
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Longtemps considéré comme une curiosité biologique, l’élimination programmée d’ADN est en réalité un phénomène répandu, observé chez des centaines de milliers
Brûler la chandelle par les deux bouts : élimination des extrémités des chromosomes chez la paramécie
buff.ly
CNRS Biologie
CNRS Biologie
Background. Paramecia belong to the ciliate phylum of unicellular eukaryotes characterized by nuclear dimorphism. A diploid germline micronucleus (MIC) transmits genetic information across sexual gene...
www.biorxiv.org
Background The ability to deposit histone H3K27-trimethyl (me3) marks is essential for transcriptional repression by Polycomb Repressive Complex 2 (PRC2). This is largely attributed to Polycomb repres...
The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of Helitrons
A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium - Genome Biology
link.springer.com
Excited to announce the upcoming Jacques Monod Conference on the mechanistic and evolutionary basis of programmed DNA elimination (Sept 21–25, 2026): cjm.sb-roscoff.fr/en/conferenc... Organized by @laurarossevo.bsky.social and myself.
3mo