Epilepsy is one of the most common neurological disorders, affecting roughly 50 million people around the world.
Researchers at Oxford are looking at how epilepsy can be prevented, diagnosed and treated ⬇️
#InternationalEpilepsyDay
Now online! Peripheral cancer attenuates amyloid pathology in Alzheimer’s disease via cystatin-c activation of TREM2
University of Oxford
Cell - a Cell Press journal
I don't know how many people see this when they look at trees during the winter, but mistletoe always reminds me of amyloid plaques - mistletoe is a parasite and each 'plaque' can vary in size. This is how I think of the 3D structure of amyloid plaques in the brain
www.pharm.ox.ac.uk/news/new-stu...
Brain cells critical for mouse navigation found to be highly specialised
www.ox.ac.uk/news/2026-06...
@oxneuro.bsky.social @medsci.ox.ac.uk
Tim Viney
New paper out in Current Biology.
We define thalamic head direction (HD) cells based on the combination of neurochemical identity, physiology, sensorimotor responses, and connectivity, suggesting cell types.
Great work led by Sara Hijazi and Shan Jiang from the lab.
www.cell.com/current-biol...
Tim Viney
Tim Viney
Tim Viney
1. Some good news at last. This week’s column is about the amazing thing a couple of us stumbled into three years ago, which we’ve now developed into a global research programme. It doesn’t change everything, of course, but it could help change quite a lot. + 🧵 www.theguardian.com/commentisfre...
Fascinating interview with @utafrith.bsky.social
www.tes.com/magazine/tea...
Thalamic recordings show a rhythm that’s strong in wake and REM and absent in deep sleep: An electrophysiological signature of conscious states.
www.nature.com/articles/s41...
#neuroscience
Coincidence of thalamic HD signal and retrosplenial visual input is detected in the Presubiculum! 🎯 This may be the neuronal basis for landmark anchoring of the HD signal. Pleased to announce the VOR is now available elifesciences.org/articles/92443 Congrats first author Louis Richevaux 🙌
Chowdhury et al. report the discovery of a 19–45-Hz thalamic oscillation that is present during human wakefulness and REM sleep, but not NREM sleep.
Nonlinear dendritic integration in single presubicular neurons provides a mechanism for combining vestibular-based head-direction signals and visual landmark signals to anchor the brain’s internal com...
Hijazi and Jiang et al. identify distinct head direction (HD) cell subpopulations
in the mouse anterodorsal thalamic nucleus, based on the combination of firing patterns,
connectivity, and neurochemic...
www.pharm.ox.ac.uk
Researchers from the Viney Group in the Department of Pharmacology, along with collaborators from The Center for Systems Neuroscience, Boston University, US, have identified distinct subpopulations of...
The autism spectrum has widened to the point of collapse, affecting how teachers should support autistic pupils in the classroom, researcher Uta Frith tells Helen Amass
I knew that a revolution in our understanding of soil could change the world. Then came a eureka moment – and the birth of the Earth Rover Program, says Guardian columnist George Monbiot
Experts at Oxford are looking at how epilepsy can be prevented, diagnosed and treated, as well as promoting awareness of the condition to reduce stigma and improve quality of life for people with epil...
Peripheral cancer inhibits amyloid pathology and rescues cognition of Alzheimer’s disease through secretion of cystatin-c (Cyst-C), which binds amyloid oligomers and activates TREM2 in microglia and enables microglia to degrade pre-existing plaques.
