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Very excited to share our new review on the complexity of SMA genetics, now online @cp-trendsgenetics.bsky.social! General interest in complex genetics? Want to know more about long-read sequencing? Segmental duplications? ✅✅✅ Have a look! www.cell.com/trends/genet...
1d
The SMN locus in the T2T era: Structure, gene conversion, and clinical implications
Long-read sequencing, paralog-aware variant calling, and telomere-to-telomere (T2T) human genome assemblies now enable the resolution of copy-, haplotype-, and nucleotide-level complexities in segment...
www.cell.com
1mo
Huntingtin polyglutamine expansions misdirect axonal transport by perturbing motor and adaptor recruitment: iScience www.cell.com/iscience/ful...
Ewout Groen
Peer-reviewed version of our study led by @aliceeseola.bsky.social first seen on @biorxiv-cellbio.bsky.social showing the exquisite level of control of organelle trafficking & autophagy exerted during plant infection by the blast fungus. Thanks to all co-authors. www.cell.com/cell-reports...
Molecular network; Molecular neuroscience; Cellular neuroscience
www.cell.com
Huntingtin polyglutamine expansions misdirect axonal transport by perturbing motor and adaptor recruitment
9d
Adam Hendricks
New preprint alert! Ever wonder if cells can talk to each other? Tunneling nanotubes (TNTs) are tiny bridges between cells used to pass organelles, nucleic acids, proteins & even viruses but we've never seen inside them clearly. Until now! 👇🧵 biorxiv.org/content/10.64898/2026.05.27.728322v1
The blast fungus forms a force-generating appressorium for plant infection. Eseola et al. show how individual spore cells adopt distinct fates, trafficking organelles to the appressorium or undergoing...
www.cell.com
Synchronous spatiotemporal control of autophagy and organelle trafficking is necessary for infection by Magnaporthe oryzae
Aga Kendrick and I are co-chairing a session, “Intracellular Transport Logistics across Scales” at #CellBio2026, December 12-16, in San Diego this year! 🔬🌞 Abstract deadline for talks is JUNE 9. To be considered for our session, select “Cytoskeleton and Motility” as a topic area. See you there!
15d