In our #journalclub, we looked at the cool new findings from Deng and colleagues, which show that the bacterial reverse transcriptase Drt3 chain B can synthesise poly(AC) DNA strands in the absence of a nucleic acid template, encoded by conserved surface amino acids.
www.science.org/doi/10.1126/...
Defense-associated reverse transcriptases (DRTs) are widespread bacterial anti-phage systems that use unconventional mechanisms of polynucleotide synthesis. We show that DRT3, which comprises two dist...
