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Hepatoblastoma is a nasty childhood liver cancer driven by mutant β-catenin How tumor cells get different and more or less aggressive? We found this out w Peng & Thomas from the Princess Maxima Center for Pediatric Oncology & @annanordin.bsky.social @liu.se @pnas.org www.pnas.org/doi/10.1073/...
The mechanisms by which Wnt/β-catenin signaling regulates gene expression in a tissue- and context-specific manner remain poorly understood, limiti...
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Differential Wnt/β-catenin signaling via TCF7L2/LEF1 binding specificity shapes cellular and tumor phenotypes | PNAS
12h
Claudio Cantù