We identified how mechanical forces shape myelin development. The TMEM63A channel in oligodendrocytes converts physical cues into molecular signals that control myelin growth.
Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry: Neuron www.cell.com/neuron/fullt...
Dereddi, Djannatian, and colleagues show that oligodendrocytes use mechanical cues
to measure axon size. The stretch-activated channel TMEM63A converts membrane tension
into calcium signals, which cal...
