We identified how mechanical forces shape myelin development. The TMEM63A channel in oligodendrocytes converts physical cues into molecular signals that control myelin growth.
Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry: Neuron www.cell.com/neuron/fullt...
Dereddi, Djannatian, and colleagues show that oligodendrocytes use mechanical cues
to measure axon size. The stretch-activated channel TMEM63A converts membrane tension
into calcium signals, which cal...
Our new issue is now out at cell.com/neuron/current. The cover is one of our favorites, featuring an illustration by the author of the study, Amit Agarwal, and his daughter Nicolo. It reimagines the oligodendrocyte as an octopus exploring corals.
