Our paper on the YprA family of helicases and their roles in bacterial defence is now out!
We describe ARMADA, a defence system synergise with Druantia and show that both systems spread horizontally on a novel type of mobile genetic element that we call SPIDERs
www.sciencedirect.com/science/arti...
www.nature.com/articles/s41...
#microsky
The activation of an antiphage defence system relies on host factors targeted by phages, a mechanism analogous to the way that eukaryotic innate immune systems detect pathogen-induced perturbations of...
www.nature.com
www.sciencedirect.com
Bacteria and archaea possess an enormous variety of antiviral immune systems that often share homologous proteins and domains. YprA-family helicases a…
Motility cessation in bacteria is a key regulatory strategy that provides multiple survival advantages including enhanced community cooperation, niche adaptation and evasion of host immune responses....
CapK is a bacterial DNA damage-activated kinase that phosphorylates transcriptional repressor CapS to control adjacently-encoded anti-phage immune pathway genes in response to a universal stress signal, DNA damage
@kevincorbett.bsky.social and colleagues
link.springer.com/article/10.1...
To Move or Not to Move: When and How Bacteria Suppress Flagellar Motility
onlinelibrary.wiley.com/doi/full/10....
#MicroSky
Bacteria encode numerous stress-response pathways that protect their hosts against both internal and external threats. A key question is how these pathways are regulated, especially anti-phage immune ...
Bacterial cell division protein FtsZ complexes with a phage protein to activate bacterial immunity
@natmicrobiol.nature.com from Michael Laub & Abel Garcia-Pino
www.nature.com/articles/s41...
www.nature.com
The activation of an antiphage defence system relies on host factors targeted by phages, a mechanism analogous to the way that eukaryotic innate immune systems detect pathogen-induced perturbations of...
🧫🌾 Ancient #soil #Bacteria may have played a key role in the development of #agriculture by influencing #nutrient cycling and #plant growth.
#Microbiology #SoilMicrobiology #Ecology #Microsky via @sciencex.bsky.social
During the Archean Eon—roughly 4 billion years ago—the Earth was a lifeless planet. The atmosphere lacked oxygen, and there were few, if any, organisms to be found anywhere on the globe. Then…
Antimicrobial resistance in Klebsiella pneumoniae is a growing global threat, but its evolutionary routes remain hard to predict. This study uses machine learning to explore how resistance evolves acr...
How do human cells defend against viruses?
@sgfern.bsky.social discovers that human immune proteins named ISGs target ancient features of replication shared between animal and bacterial viruses – opening analysis of human immunity to the power of bacterial genetics
www.biorxiv.org/content/10.6...
