Published! Biallelic OSMR deficiency is a new Primary Atopic Disorder. A rare disease that provides new insights into the mechanisms of human allergic disease.
A wonderful international team effort.
Turvey Lab
New human primary atopic disorder defined: In @jhumimmunity.org, Samra and Sharma et al. show OSMR deficiency disrupts OSM-STAT signaling, driving severe early-onset #eczema, #eosinophilia, and elevated IgE. rupress.org/jhi/article/...
#Immunology #Genetics #Atopy #IEIs
@turveylab.bsky.social
