Exploring brain cell biology, organelle dynamics & proteostasis.
📍University of Cambridge @cambridge-uni.bsky.social | @UKDRI | 🔬developing live cell biosensing tech
Avezov lab
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simple it wasn’t :)
🧪 Biomedical Picture of the Day from the Presynapse -
The more we learn about #glycotime, the more dramatic will be our revisions to textbooks on such basic principles as protein trafficking and organelle privileges
www.nature.com/articles/s41...
Researchers have identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation.
https://scim.ag/4nTQ3nq
This mesmerizing timelapse captures the nonstop motion inside an animal cell. Red/orange streaks are the growing ends of microtubules, tiny “highways” that can rapidly assemble and disassemble to move proteins & other molecules within the cell.
📸: Andy Moore, HHMI’s Janelia Research Campus
Nice very interesting idea.
These fields are moving fast, with real momentum and discovery ahead — whoever takes this on will have plenty to be excited about!
🚨📜Our new paper out in @AdvSciNews:
ER shape matters for neuronal health - disrupting ER continuity halts neuro-firing as it slows Ca2+ store refill, explaining selective neuronal vulnerability to ER problems in neurodegeneration 🧠
a thread to follow advanced.onlinelibrary.wiley.com/doi/10.1002/...
My choice last week in @science.org
Deltaviruses spread through a viral Trojan Horse
10.1016/j.cell.2026.01.037
Just published in @science.org
The oscillatory biology of sleep: Linkage to dementia | Science www.science.org/doi/10.1126/...
During wakefulness, neuromodulators operate largely independently to support behavior and cognition. By contrast, sleep reorganizes their activity into a coordinated brain rhythm. During sleep, the ma...
www.science.org
Tang, Dai, Qing, Zhang and colleagues describe a role for N-glycosylation in the nucleus: N-glycans modify inner nuclear membrane proteins, and the modification is implicated in the maintenance of H3K...
