Congratulations @sophiemartinlab.bsky.social group for your latest publcation in @natcomms.nature.com Phosphoregulation of the novel hemi-arrestin MAPK scaffold Sms1 prevents untimely mating @mocel.bsky.social @sciencesunige.bsky.social
Arp2/3-dependent actin assembly shapes endosomes and promotes intracellular trafficking in fission yeast
The work from Alejandro Melero @ameleroc.bsky.social and Miguel Basante-Bedoya just out in Current Biology.
www.sciencedirect.com/science/arti...
@biology-unige.bsky.social
This protein is essential for cells to communicate with a mating partner. Its discovery also reveals that diverse organisms use convergent pathways (with likely distinct evolutionary origins) to solve the same signalling problem.
As initially presented on Biorxiv: bsky.app/profile/soph..., but with a new figure, where we probe pheromone-induced polarized growth.
"Humbled to receive this recognition. This belongs as much to my team, my family, & to my home, Palestine: the people, the place, the joyful stubbornness to enjoy life."
Cheers buddy @gautamdey.bsky.social
Thx to my mentors @sophiemartinlab.bsky.social, @paveltomancak.bsky.social, & Pierre Gönczy.
Endosomes serve as crucial sorting centers that streamline the distribution of cell surface proteins. The early endosome receives traffic from both th…www.sciencedirect.com
Distinct #Cdc42 protein levels differentially regulate polarized growth and cell fusion in Schizosaccharomyces pombe
The work of @sajjitasaha.bsky.social and @aiswaryasajeevan.bsky.social, with Laura Merlini and Vincent Vincenzetti, now out in @plosbiology.org !
@biology-unige.bsky.social
Sophie G Martin
Sophie G Martin
Sophie G Martin
How do cells communicate? They use Sms1 ! 🙂
More seriously, Sms1 is the scaffold of the pheromone-MAPK signalling cascade in fission yeast, which @borissieber.bsky.social et al discovered.
Have a look at the paper 👇
@biology-unige.bsky.social
How do cells communicate? They use Sms1 ! 🙂
More seriously, Sms1 is the scaffold of the pheromone-MAPK signalling cascade in fission yeast, which @borissieber.bsky.social et al discovered.
Have a look at the paper 👇
@biology-unige.bsky.social
How do cells communicate? They use Sms1 ! 🙂
More seriously, Sms1 is the scaffold of the pheromone-MAPK signalling cascade in fission yeast, which @borissieber.bsky.social et al discovered.
Have a look at the paper 👇
@biology-unige.bsky.social
Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦
The lab is on a roll. 2nd preprint in as many weeks!
High levels of Cdc42 GTPase underlie an all-or-none decision to fuse.
Great team effort led by PhD students @sajjitasaha.bsky.social and @aiswaryasajeevan.bsky.social
www.biorxiv.org/content/10.1...
@biology-unige.bsky.social
Congratulations to Gautam Dey (EMBL) and Omaya Dudin (University of Geneva) for being awarded the EMBO Gold Medal 2026 in recognition of their outstanding contributions to the #LifeSciences in Europe! 🧪 https://www.embo.org/press-releases/embo-gold-medal-2026-awarded-to-gautam-dey-and-omaya-dudin/
Cdc42 is a Rho-family GTPase conserved across eukaryotes, where it plays essential roles in cell polarization. In single-celled yeast systems, Cdc42 is a key driver of symmetry breaking and polarized ...
www.biorxiv.org
This study identifies the hemi-arrestin Sms1 as the essential scaffold for mitogen-activated protein kinase (MAPK) signalling in fission yeast mating. Phosphorylation detaches Sms1 from the plasma mem...
This study identifies the hemi-arrestin Sms1 as the essential scaffold for mitogen-activated protein kinase (MAPK) signalling in fission yeast mating. Phosphorylation detaches Sms1 from the plasma mem...
This study identifies the hemi-arrestin Sms1 as the essential scaffold for mitogen-activated protein kinase (MAPK) signalling in fission yeast mating. Phosphorylation detaches Sms1 from the plasma mem...
Polarized growth in #Spombe needs Cdc42, but what role does it play in cell fusion? @sajjitasaha.bsky.social @sophiemartinlab.bsky.social &co show that mitotic polarized growth responds linearly to Cdc42 levels, but mating involves a sharp switch-like response @plosbiology.org 🧪 plos.io/4bvGIhb
EMBO
Very excited that our discovery of Sms1 as the #MAPK #scaffold of fission yeast mating has just been published in @natcomms.nature.com!
@biology-unige.bsky.social
www.nature.com/articles/s41...
Very excited that our discovery of Sms1 as the #MAPK #scaffold of fission yeast mating has just been published in @natcomms.nature.com!
@biology-unige.bsky.social
www.nature.com/articles/s41...
Very excited that our discovery of Sms1 as the #MAPK #scaffold of fission yeast mating has just been published in @natcomms.nature.com!
@biology-unige.bsky.social
www.nature.com/articles/s41...
