My first week as an intern at Genentech has been such an amazing experience! 🧬
I'm thrilled to be working in the Infectious Diseases Department, under the guidance of Dr. Eric M. Kofoed in the Man-Wah Tan Lab. The energy and science here are so inspiring, and I can't wait to dive deeper
Biofilm Starter Pack on the Blue place
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Had a chance to present my work at the Gordon Research Conference on Microbial Adhesion and Signal Transduction. I'm so grateful for this opportunity to listen to inspiring talks, make new connections, receive advice, and engage in meaningful discussions in such a dynamic and supportive environment!
In this work, we identify DbfQ, a small periplasmic protein that serves as a key regulator of the DbfRS two-component system, coordinating broad physiological adaptations in Vibrio cholerae.
Check out our lab's latest work in @plos.bsky.social, which reveals biofilm dispersal patterns using FAP-fluorogen labeling approach.
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We show that outer membrane stresses activate the DbfQRS pathway, rewiring global gene expression across biofilms regulation, central metabolism, and stress responses, with measurable fitness costs in an infection model - highlighting DbfQRS as a potential target for anti-infective strategies
Honored to have presented my work on the DbfQRS pathway at the 2025 #ASMBiofilms Conference! Sharing research from the Bridges Lab and connecting with many brilliant minds in the field was such an inspiring experience. Grateful for the opportunity and energized for what's next!
Thrilled to share that my first-author paper is now published in Nature Communications! 🎉 Huge thanks to my PI, Dr. Drew Bridges (@bridgesbio.bsky.social), my collaborators, and all the incredible lab members for their support throughout this project
www.nature.com/articles/s41...
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Welcome refugees from X! Follow microbiologists and more in the @binningsingletons.com and Friends Starter Pack!
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Emmy Nguyen
Ákos T Kovács
Emmy Nguyen
Emmy Nguyen
Emmy Nguyen
Emmy Nguyen
A two-component system, DbfRS, regulates biofilm formation in Vibrio cholerae. Here, Nguyen et al. identify a small periplasmic protein that controls the activity of the system’s receptor, and show th...
