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After 1.5 years of work in @kauralasoo.bsky.social’s lab, we finally published my preprint! We introduce gpu-coloc, a GPU-accelerated implementation of coloc, show comparability to CLPP and aim to provide practical guidelines. Now accessible on BioRxiv: www.biorxiv.org/content/10.1...
9mo
Colocalisation is a powerful approach to assess if two genetic association signals are likely to share a causal variant. However, association analyses in large biobanks and molecular quantitative trai...
www.biorxiv.org
Ultra-fast genetic colocalisation across millions of traits
Happy to share that this work led by @mihkeljesse.bsky.social has now been published at PLOS Genetics! journals.plos.org/plosgenetics... A couple of thoughts below.
14h
Author summary Over 90% of human genetic variants associated with human traits and diseases lie in non-coding regions of the genome, making it difficult to interpret the mechanisms by which these vari...
journals.plos.org
Ultra-fast genetic colocalisation across millions of association signals
Kaur Alasoo
After 1.5 years of work in @kauralasoo.bsky.social’s lab, we finally published my preprint! We introduce gpu-coloc, a GPU-accelerated implementation of coloc, show comparability to CLPP and aim to provide practical guidelines. Now accessible on BioRxiv: www.biorxiv.org/content/10.1...
9mo
www.biorxiv.org
Colocalisation is a powerful approach to assess if two genetic association signals are likely to share a causal variant. However, association analyses in large biobanks and molecular quantitative trai...
Ultra-fast genetic colocalisation across millions of traits