Happy to share our latest work on bridge lipid transfer proteins, by PhD student @yarasayed1.bsky.social. A great collaboration with @ungermannlab.bsky.social @arnemoeller.bsky.social and Reggiori lab!
Vanni Lab at UNIFR, Switzerland
Atg18 interaction positions Atg2 for efficient lipid transfer into phagophore elongation
Sabrina Chumpen Ramirez, @dmitryshvarev.bsky.social et al
link.springer.com/article/10.1...
During macroautophagy, the de novo formation of the autophagosome at a membrane contact site (MCS) with the endoplasmic reticulum requires directional lipid flux for the growth of the initial phagopho...