//
sign in
Post
by @danabra.mov
PostEmbed
by @danabra.mov
Record
by @jimpick.com
Record
by @atsui.org
+ new component
Post
📰 Great "First Reactions" by @aprillukowski.bsky.social featuring C-GEM's recent thioribose work! pubs.acs.org/doi/10.1021/...
Mar 27, 2025
Thioesters, rather than oxo-esters, can be tolerated and processed during translation to incorporate unnatural monomers.
pubs.acs.org
Promiscuity in Nature Extends to Central Protein Biosynthetic Machinery
C-GEM, the NSF Center for Genetically Encoded Materials
✨ New from C-GEM in ACS Central Science: Thioesters Support Efficient Protein Biosynthesis by the Ribosome pubs.acs.org/doi/10.1021/... Congrats to Alexandra & Jacob, along with Isaac, Jess, @alexsolivan.bsky.social, @nxhamlish.bsky.social, Katie, Alanna, Jamie, and Scott! #NSFfunded @pubs.acs.org
Feb 3, 2025
Thioesters are critical chemical intermediates in numerous extant biochemical reactions and are invoked as key reagents during prebiotic peptide synthesis on an evolving Earth. Here we asked if a thio...
pubs.acs.org
Thioesters Support Efficient Protein Biosynthesis by the Ribosome
C-GEM, the NSF Center for Genetically Encoded Materials