Implications of successive blood feeding on #dengue virus inhibition by Wolbachia in Aedes aegypti mosquitoes
@entomososwin.bsky.social @mallerybreban.bsky.social @brackneylab.bsky.social @chantalvogels.bsky.social @yaleemd.bsky.social
🦟📄 New preprint! Our first large-scale phylodynamic study of Jamestown Canyon virus (JCV) reveals how mosquito ecology shapes the evolution, persistence, and spread of this understudied arbovirus in North America.
Read it here! www.biorxiv.org/content/10.6...
Ellie Bourgikos
Ellie Bourgikos
Nature Communications
Check out our new print that combines dense sequencing and phylodynamics to uncover a bunch of 😎 things about an understudied virus.
- Doesn't evolve for 10 months a year ✅
- Uses some mossies for maintenance, others for spread ✅
- Established in Northeast for ~300 years ✅
Great to collaborate with @chantalvogels.bsky.social, Afeez Sodeinde and their team on this comprehensive work looking at dengue virus & Wolbachia interactions, making the case for considering DENV genetic diversity when implementing Wolbachia-based control interventions - key findings below! 🦠🦟
Variations in annual dengue intensities are explained by temperature anomalies
Our new work led by Abbey Porzucek, @rafalpx.bsky.social, @colincarlson.bsky.social, Dan Weinberger to develop a method to compare relative dengue intensity between years and countries.
www.medrxiv.org/content/10.6...
Nathan Grubaugh
Emilie Finch
Nathan Grubaugh
🦟📄 New preprint! Our first large-scale phylodynamic study of Jamestown Canyon virus (JCV) reveals how mosquito ecology shapes the evolution, persistence, and spread of this understudied arbovirus in North America.
Read it here! www.biorxiv.org/content/10.6...
Ellie Bourgikos
Dengue virus transmission by Ae. aegypti mosquitoes poses a significant public health threat, necessitating innovative control strategies. Here, the authors demonstrate that, while successive blood feeding increases earlier dengue virus dissemination, the inhibitory effects of Wolbachia remain strong, highlighting Wolbachia’s potential to disrupt dengue transmission under natural feeding conditions.
bit.ly
Jamestown Canyon virus (JCV) is a re-emerging mosquito-borne virus of increasing concern in North America. It has been historically understudied, leading to significant gaps in our understanding of it...
Jamestown Canyon virus (JCV) is a re-emerging mosquito-borne virus of increasing concern in North America. It has been historically understudied, leading to significant gaps in our understanding of it...
📢New preprint on the impact of dengue virus genetic diversity on inhibition by Wolbachia 🦟🦠🧬
Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨
Key findings in thread below 👇
www.biorxiv.org/content/10.1...
Chantal Vogels
The release of Aedes aegypti mosquitoes transinfected with the virus-inhibiting Wolbachia bacterium has the potential to reduce the burden caused by dengue virus (DENV). However, the robustness of thi...
