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Very excited to share our new preprint, led by Alyssa Henderson! We ask why auxotrophy is so widespread in bacteria, and find that phylogeny is the dominant predictor of autotrophy, as opposed to environmental context. Check it out! 👇
Belatedly sharing an opinion piece with Kuni Kaneko. We propose that 𝘁𝗵𝗲 𝗰𝗲𝗻𝘁𝗿𝗮𝗹 𝗱𝗼𝗴𝗺𝗮 is one instance of a more general pattern that has evolved repeatedly across levels of biological organisation. doi.org/10.1098/rstb...
Evolution induced state shifts in a long-term microbial community experiment (now out, but previously posted here as a preprint) with Ville Mustonen, Lutz Becks @jcairns.bsky.social & others. Experiment continues @utu.fi and now 5+ years www.pnas.org/doi/10.1073/...
Viruses are highly abundant in the oceans, but there is one place you won't typically find them: in global ocean ecosystem models... until now. Introducing "vDarwin", an explicit integration of viruses into the MITgcm/Darwin global ecosystem framework: www.biorxiv.org/content/10.6... a 🧵
New preprint! 🚨 Phage proteins don't act alone. Phages rely on homooligomerisation to assemble identical protein subunits into functional forms. But figuring out those exact configurations experimentally is tough. Learn about our approach in our new preprint! 👇 (1/n) www.biorxiv.org/content/10.6...
I’ve started Academic Renewal, a Substack on research culture, scholarship and the pursuit of knowledge. The first post asks how private concerns about academic life might become an open conversation about incentives, assessment and responsibility. academicrenewal.substack.com/p/why-academ...
Thrilled that our paper "Eco-evolutionary dynamics of massive, parallel bacteriophage outbreaks in compost communities" is out! 🎉🦠🧬 www.science.org/doi/10.1126/... w/ @paulbrainey.bsky.social, Petros Skiadas, Paulien Hogeweg, @bedutilh.bsky.social
Pleased to see this beautiful paper out. Kudos to @jeroenmeijer.bsky.social who took @stevenquistad.bsky.social data and dug deep, revealing a new phage that erupts to astonishing abundance. As theory predicts, the life of SGEs is fuelled by encounters with new hosts www.science.org/doi/10.1126/...
New in Science Advances: A bacteriophage stayed genetically stable for months, then evolved rapidly in a new microbial community. www.evolbio.mpg.de/3884217/viru... @jeroenmeijer.bsky.social @paulbrainey.bsky.social @uni-jena.de @utrechtuniversity.bsky.social @bedutilh.bsky.social
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Biological communities are complex, dynamic systems that underpin ecosystem functionality, yet their long-term dynamics and predictability remain p...
www.pnas.org
www.biorxiv.org
Evolution induced state shifts in a long-term microbial community experiment | PNAS
Amino acid auxotrophy is a feature of a distinct bacterial lifestyle across environments
Amino acid auxotrophy, the loss of biosynthetic potential for an amino acid, is a highly prevalent feature of microbial life, yet the evolutionary processes driving its distribution in nature remain u...
doi.org
Abstract. The central dogma of molecular biology, as originally proposed by Crick, asserts that information passed into protein cannot flow back out. This
doi.org
From private concern to shared conversation
academicrenewal.substack.com
Generalizing the central dogma as a cross-hierarchical principle of biology
Why academic renewal?
A single bacteriophage can dominate microbial communities yet only evolves when migration changes its ecological context.
www.science.org
A single bacteriophage can dominate microbial communities yet only evolves when migration changes its ecological context.
www.science.org
Eco-evolutionary dynamics of massive, parallel bacteriophage outbreaks in compost communities
Eco-evolutionary dynamics of massive, parallel bacteriophage outbreaks in compost communities
Nobuto Takeuchi
Susie Grigson
Joshua Weitz
Teppo Hiltunen
Microbial Systems Ecology Lab
Jeroen Meijer
MPI for Evolutionary Biology
Paul Rainey
Paul Rainey
No doubt the dog was only optimized for clarity and presentation.