🧵 New preprint out! We asked: what happens to gut bacteria when the intestine is under chronic inflammation (IBD)? Turns out, the host's inflammatory state reshapes how they evolve, and the results are pretty striking. A thread 👇
Extensive transduction events lead to hybrid clones that form a new genetic lineage, establishing itself in the IBD gut. On top of that, high levels of recombination between prophages point to major impacts in viral evolution. 🦠🔬
www.biorxiv.org
#Microbiology research requires a stable, unified #taxonomy of bacterial strains. In this Essay, Federica Palma, @sylvainbrisse.bsky.social and co-authors discuss the LIN system, resolving communication issues for precise strain definitions and epidemiological tracking. 🧪 #AcademicSky
bit.ly/4xrMs4r
Marta Lourenço
Marta Lourenço
PLOS Biology
Chronic inflammation doesn't just affect you! It's actively steering the evolution of your gut microbiome. Phages and gene transfer between bacteria may play a much bigger role in IBD than we previously appreciated.
