Infectious Diseases doctor (at UCLH) and academic (at UCL). Research focuses on host-pathogen interactions in TB, leprosy and UTIs. What are the immune, epithelial and stromal cell responses involved, and could they be targets for host-directed therapies?
Gabriele Pollara
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Fascinating paper.
Not only association between auto antibodies against immunotegulatory IL-10 and some patients with inflammatory bowel disease.
But also association between these antibodies and HLA risk allele for IBD. What's mechanistic link?
#immunosky #MedSky
www.nejm.org/doi/full/10....
Fascinating paper.
Not only association between auto antibodies against immunotegulatory IL-10 and some patients with inflammatory bowel disease.
But also association between these antibodies and HLA risk allele for IBD. What's mechanistic link?
#immunosky #MedSky
www.nejm.org/doi/full/10....
Run, cycle, or trek to support those affected by leprosy! Join our challenge events for unforgettable experiences that transform lives. Book your place today: www.lepra.org.uk/events/category/challenge-events
#ChallengeEvents #RunForACause #CycleForChange #TrekForGood #MakeADifference
🆕💥🔴Review summarizes recent clinical trials for treatment of tuberculous meningitis
🔺Disappointing result:high dose Rifampin HARVEST
🔺The only adj Rx supported is dexamethasone(may not be universal: HIV+, ACT HIV, no survival benefit)
🔺Several ongoing RCTs #idsky
www.tandfonline.com/doi/full/10....
Our June issue is now live.
The cover image puts microbes at play.
Have your own fun and enjoyment reading the content within:
www.cell.com/cell-host-mi...
Gabriele Pollara
Gabriele Pollara
Antibiotic Steward 🅱️C🆔🅿️🌟
The fine balance of prophylactic antibiotics.
Prevent infections but are these infections significant and at what cost (resistance)?
Here in stem cell transplants, but also relevant to other settings #IDSky #UTISky #AMR #ClinMicro
academic.oup.com/ofid/advance...
Lepra UK
Excited to share my first-author research letter! Our findings highlight an important question: how therapies perform outside of clinical trials, particularly among patients often underrepresented in research. Thank you @jamanetworkopen.com!
@unmccom.bsky.social @unmc-id.bsky.social
So much we need to learn about tick-related infections, so this effort by HHS is welcome.
But I worry deeply about the company they keep in their announcement. More here: #IDSky #Medsky
voices.nejm.org/doi/full/10....
Cell Host & Microbe
The current #Ebola outbreak in DRC has the potential to be even larger than those in 2018 and 2014. Why have we seen larger outbreaks in recent years? There are multiple reasons including conflict, population movement and urbanization. But the trend shows we must learn how to respond better
