Can we rewire how plants fight disease? We used AF3 to predict, validate, and engineer a sensor–helper interface that escaped biochemistry for years 🤯
Grateful to @mpcontreras.bsky.social & @kamounlab.bsky.social for trusting me to be part of this story.
Full story below👇🏻
www.biorxiv.org
Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade 🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇
Video
Mauricio Contreras
Maián
A conserved structural logic underlies sensor-helper NLR communication in the NRC immune receptor network https://www.biorxiv.org/content/10.64898/2026.05.18.725810v1
