How short can a degron be?
A compact, genetically encoded, 9-aa tunable degron that drives MDM2-dependent degradation enabling precise control of protein levels from yeast to human cells.
Thanks to @eswarappalab.bsky.social for the opportunity to explore this in yeast.
#Degron #Yeast #CellBiology 🧬
Saravanan Palani
Interested in tunable protein degradation? Check out our new preprint describing a compact, portable degron derived from MTCH2: doi.org/10.64898/202...
Led by Lekha EM
Saubhik Som
Ramon Boro
Sandeep Eswarappa
Great collaboration w/ Anubhav Dhar
Eepsitha
@syncellbiolab.bsky.social
#iiscbangalore
