We first optimized differentiation of #iPSCs into #BBB cell types and performed in-depth characterization using RNA-seq and #proteomics, benchmarking them against primary cells. The results are available in our new database 💻 check it out here: dbneurovasp.isd-muc.de
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I’m very excited to share that one of the main papers from my PhD with Katalin is now out in @natneuro.nature.com
We developed a fully #iPSC-derived model of the #blood-brain-barrier #BBB to study neurovascular disorders!
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Very happy that @nature.com selected our picture! Thanks a lot 🥰
We then used those cells to build our fully iPSC derived #BBB model. Read the full story 📚 here: www.nature.com/articles/s41...
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New paper out today at @natneuro.nature.com in collab. with DichgansLab @isd-research.bsky.social @lmumuenchen.bsky.social: We developed a fully #iPSC-derived human model of the #BBB #blood-brain-barrier and applied it to study neurovascular disease (NVD)! #OA PDF here: rdcu.be/eUIl3 Thread👇 1/10
Huge thanks to all the co-authors and collaborators at @isd-research.bsky.social and @paquetlab.bsky.social!
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Image of the Week: Congrats to the team of González-Gallego J et al., Nat Neurosci. 2026 for this lovely award in Nature Briefing 🏆 🖼️ @judit-gonzalez.bsky.social @paquetlab.bsky.social (->Fig 2b www.nature.com/articles/s41...)
PaquetLab
New paper out today at @natneuro.nature.com in collab. with DichgansLab @isd-research.bsky.social @lmumuenchen.bsky.social: We developed a fully #iPSC-derived human model of the #BBB #blood-brain-barrier and applied it to study neurovascular disease (NVD)! #OA PDF here: rdcu.be/eUIl3 Thread👇 1/10
