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Excited to share this new preprint from a large collaborative effort using #exome + #genome sequencing, moving beyond GWAS to implicate 68 genes in #IBD through rare protein-coding variation. bit.ly/43h72GA @broadinstitute.org @mgbresearch.bsky.social
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Inflammatory bowel disease (IBD) is a chronic immune-mediated disorder of the gastrointestinal tract whose genetic basis is only partly resolved because most risk variants identified by genome-wide as...
Exome sequencing directly implicates 68 genes in inflammatory bowel disease