We found and validated in vitro that early-life perturbations (hypertonic saline inhalation therapy) can select for microbial traits linked to salt and antibiotic tolerance.
www.cell.com/cell-host-mi...
#antibiotics
#cysticfibrosis
#microbial
@broadinstitute.org @mgbresearch.bsky.social
Steinberg et al. generated an infant nasal microbial gene atlas using samples from
infants with and without cystic fibrosis. Frequent hypertonic saline inhalation reshapes
airway microbiome function, ...