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🚨New paper alert! Using single molecule TIRF microscopy, we show that Nop1 destabilizes RNA structure via transient, nonspecific interactions — until specific assembly of native ribosomal complexes takes over. Congrats, Wilson! 🎉 academic.oup.com/nar/article/...
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Abstract. The liquid–liquid phase-separated environment of the eukaryotic nucleolus is proposed to benefit ribosome assembly by chaperoning rRNA folding an
academic.oup.com
Fibrillarin/Nop1 perturbs RNA folding and assembly independently of liquid–liquid phase separation
Woodson Lab