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Coordinated Representational Drift Across the Mouse Cortex https://www.biorxiv.org/content/10.64898/2026.05.05.723038v1
▶️ In our new @plosbiology.org study with James Poulet, we show somatosensory contributions to M1 Vm in a forelimb reaching task. ▶️ Surgical removal of somatosensation impacted movement encoding, Vm regulation and its transition to active state, and more! ▶️ Learn more: doi.org/10.1371/jour...
1/ 97% of cortical PNNs are on PV interneurons. But PNN-positive and PNN-negative PV cells don't split into two groups — they sit at different ends of a transcriptional continuum of fast-spiking specialization. New preprint 🧵
www.nature.com/articles/s41... Two-author papers are always special. Using optogenetic stimulation of hippocampal synapses in awake mice and tracking them over approx. 2 weeks, we link synaptic strength, spine volume and their stability. It's confirmed: bigger spines are stronger and more stable 😅