By comparing fMRI to LFP coherence one thing stood out
▶️ low-frequency coherence (<4 Hz) consistently tracked fMRI effects across all manipulations! Higher frequencies also change (sometimes a lot), but they don’t covary with fMRI. So slow neuronal coupling is the common denominator of fMRI!
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Notably, biophysical modelling supports this framework. Using a simple three-node model we found that local excitability changes are sufficient to reproduce the direction of the low-frequency coherence effects across perturbations.
This offers a plausible mechanistic account of our results!
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