Proof of principle vs. translational reality check: Can we accumulate nano-formulated drugs inside solid tumours by transiently disrupting tumour vasculature? Yes, in principle, but with a translational catch 👇
#GO-Bio #BMFTR @lmu.de; #ChemBio bpspubs.onlinelibrary.wiley.com/doi/10.1111/...
Background and purpose Nano-formulated chemotherapeutics prolong systemic availability of drugs and can reduce systemic toxicity, but their accumulation in solid tumours is often limited and unpredi...
