Check out our new protocol paper on molecular recording of transcriptional events in genomic DNA!
Super fun pulling this together with @jennynathans.bsky.social @chenomics.bsky.social and @jshendure.bsky.social
Troy McDiarmid
New Article! Multichannel genomic recording of biological information with ENGRAM
Nature Protocols, Published online: 11 February 2026; doi:10.1038/s41596-025-01322-wThis Protocol details the use of enhancer-mediated genomic recording of activity in multiplex (ENGRAM) for molecular recording. This system converts the transient activity of cis-regulatory elements into stable genomic records that can be retrospectively recovered via DNA sequencing.