Really important development in improving contrast in the painfully low contrast images we get out of a cryo-TEM
Just look at this: laser phase plate in action!
I'm excited that this collaborative work with Alan @acartmell47.bsky.social is finally out. We have developed some powerful tools to study carbohydrate sulfatases (a tricky class of enzyme!) and shown how they can be used with enzymes from host-associated bacteria.
Not being dramatic, but this probably signals the effective end of Chemistry in English Universities.
An *efficient* Department loses something like £2k per Chemistry student per year; this change will roughly double that loss. Universities would be mad to keep teaching Chemistry.
Extract: The Novo Nordisk Foundation Center for Protein Design at the University of Copenhagen seeks to appoint two group leaders in de novo protein design. Candidates should have strong backgrounds in computational and/or experimental protein design and an ambitious research and teaching plan.