Molecular biologist | Wellcome Trust Senior Fellow | antiviral defence | RNA processing | interferons | transposable elements | small RNAs | embryonic development
Free Palestine 🍉
Sara MaciasRNA
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Speaking about miRNAs and disease for the first 22q11.2 syndrome meeting in Andalucia, Spain
canal.ugr.es/noticia/i-jo...
Our last manuscript is out! 🚨
We identify double stranded RNAs in embryonic stem cells - full of transposons, especially young LINEs and LTRs 🧐
🧬Happy Friday Reading🧬
At the 1st meeting of 22q11.2 syndrome in Andalucia. An honour to have been invited to contribute. Looking forward to the discussion
Thanks to @herassr.bsky.social @aula22andalucia
A great collaboration of my group with @herassr.bsky.social and @heick.bsky.social groups searching for mammalian dsRNAs and their importance to human disease 🧬
Some initial reactions to the 'published on a Sunday afternoon' letter from the CEO of UKRI. 🧵
www.ukri.org/news/open-le...
Registrations are now OPEN! Join us in Newcastle for the “RNA in Physiology and Disease” conference, an international meeting bringing together world-leading RNA biologists and emerging researchers.
Early bird deadline: 1 May
Abstract deadline: 30 June
Register now: genetics.org.uk/events/rna-i...
📣 POSTDOC position available in the Feschotte Lab at Cornell to work on #TRANSPOSONS! More details below. Pls send informal application or inquiry ASAP by DM or email to cf458_at_cornell.edu.
Pls spread the word 🙏 #TEsky
www.thefeschottelabatcornell.com
I'm so happy to share our latest paper! Now out in @narjournal.bsky.social 🥳
Did you know that transposable elements embedded in mRNAs can form dsRNA and activate innate immunity? 🧬🦠 Have a look! academic.oup.com/nar/article/...
#TEsky #RNAsky #RNAbiology #immunity #NAR
Sara MaciasRNA
Ahora que tengo un poco más de tiempo voy a intentar explicar los resultados del último artículo de nuestro grupo de investigación, en el que intentamos responder a la siguiente pregunta:
¿Cómo evitan nuestras células que su propio ARN active una alarma inmunológica? 🧬⚠️ (1/25)
Graphical abstract from our new paper in Nucleic Acids Research with @saramaciasrna.bsky.social 🧬
DGCR8 prevents accumulation of endogenous dsRNA derived from Alu elements within mRNAs, avoiding aberrant activation of the interferon response.
academic.oup.com/nar/article/...
Abstract. The type I interferon (IFN) response is the main innate immune pathway against viruses in mammals. This pathway must be tightly regulated to prev
