Graphical abstract from our new paper in Nucleic Acids Research with @saramaciasrna.bsky.social 🧬
DGCR8 prevents accumulation of endogenous dsRNA derived from Alu elements within mRNAs, avoiding aberrant activation of the interferon response.
academic.oup.com/nar/article/...
Abstract. The type I interferon (IFN) response is the main innate immune pathway against viruses in mammals. This pathway must be tightly regulated to prev
