Check it out, this is a truly useful dataset! #mevosky
In celebration of good friends and collaborators Erin Gloag @sirmicrobe.bsky.social, Dan Wozniak and @nanamikubota.bsky.social, here's a cool new study about rapid P. aeruginosa adaptation in wounds, with some hidden phage phun as bonus.
journals.asm.org/doi/10.1128/...
What if multireplicon plasmids are not an oddity, but an evolutionary strategy?
We found that they are common, more mobile, broader-host-range, and enriched in AMR.
Even more interesting: their assembly doesn’t look random. 👀
Paper preprint: www.biorxiv.org/content/10.6...
Thread below!🧵👇
🚨 New preprint from the lab! 🚨
We show that multireplicon plasmids are true AMR "jack-of-all-trades":
Widespread, highly mobile, broad host-range, and packed with resistance genes.
Far from random, they form co-evolving associations driven & 𝘮𝘢𝘪𝘯𝘵𝘢𝘪𝘯𝘦𝘥 by IS elements.
See Nacho's thread below!👇👇
New paper out! 🔈
Genomic Characterization of the RyC collection: 50 Multidrug Resistant Clinical Isolates of Escherichia coli and Klebsiella spp.
50 MDR gut isolates, 2 sequencing platforms, 4 “omes,” and 1 mission: provide a resource to decode AMR and MGE dynamics
www.biorxiv.org/content/10.6...
Multiple fully funded PhD/postdoc positions available: experimental evolution of tumour suppression, egalitarian & fraternal ETIs, jumbo phage ecology & genetics. Related EoIs welcome.
Email CV/statement of motivation written in own words. Open until filled.
Grateful for reposting 🙏