Excited to share our new #preprint uncovering how early human forebrain is patterned.
Compared to mouse, human dorsoventral and anteroposterior telencephalon patterning is strikingly delayed, which is correlated with SHH and FGF signalling differences.
Read it here: www.biorxiv.org/content/10.6...
Excited to share our new publication on the mechanics of cranial neural tube closure. A really enjoyable and fruitful collaboration bridging Developmental Biology and biophysical modelling. Take a look here!
www.cell.com/current-biol...
Cytoplasmic lattices are a highly abundant and essential structure in mouse oocytes and embryos. Our in situ structure from early mouse embryos provides a new insight into their molecular achitecture and function. Check it out: www.biorxiv.org/content/10.6...
It was our pleasure to have @emaniou.bsky.social at @universitypress.cambridge.org talking about her recent ongoing work as a group leader in @dublincityuni.bsky.social.
We have a new lab photo. Busy times in the Delas Lab!
Last month Maria and Shaun joined us to start their PhDs.
Learn more about our research and our team: delaslab.com
We will be recruiting another postdoc next year so have a look through our recent work and get in touch if you are interested.
Which features of tissue flows are most robust and how do they emerge from #EpithelialMechanics?
I’m @alex-plum.bsky.social (@mattiaserra.bsky.social group) and I’ll be sharing some papers on characterizing and controlling avian gastrulation flows.
PhD position available in our team @dublincityuni.bsky.social from September. Please share/ contact me for informal enquiries.
📢Our latest preprint list is now up on FocalPlane.
This week’s list focusses on research using microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included.
focalplane.biologists.com/2025/06/27/m...
Excited to share I’m starting my group in Dublin this September, supported by a Research Ireland Pathway award. We will work on neurulation mechanics using chicken embryos and human iPSCs. Looking forward to this new adventure! #newPI #womeninSTEM
2. iPSC neuroepithelial models by @hpscenthusiast.bsky.social identifying a patient mutation in VANGL2 which diminishes apical constriction in this human model
www.biorxiv.org/content/10.1...
Video
Video
Pérez-Verdugo et al. show that hindbrain neuropore closure is driven by surface ectoderm
actomyosin purse-string tension and active migration. These forces create reproducible
patterns of cell elongat...
Minister for Further and Higher Education, Research, Innovation and Science, James Lawless, has today announced €23 million in funding to support early-career researchers through the Research Ireland Pathway Programme. Read more: www.researchireland.ie/news/pathways/ #ResearchIreland
Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...
