The paper:
www.cell.com/neuron/fullt...
And the press releases:
- In English
www.ox.ac.uk/news/2026-06...
- And in French
www.insb.cnrs.fr/fr/cnrsinfo/...
New unit paper: "A learning-evoked slow-oscillatory architecture paces population activity for offline reactivation across the human medial temporal lobe" published in @cp-neuron.bsky.social www.bndu.ox.ac.uk/papers/learn...
www.cell.com
Causse et al. identify a learning-evoked slow-oscillatory architecture in the human
medial temporal lobe. Transient hippocampal 2-Hz bursts pace neuronal spiking and
synchronize gamma-band activity ac...
How does the human brain turn new experiences into memories? Causse et al. found that memory processing evokes transient, slow-oscillatory bursts in the human hippocampus. These bursts coordinate neur...
🥁We discovered that learning evokes brief 2-Hz oscillatory bursts in the hippocampus.
These bursts coordinate neuronal activity across the medial temporal lobe and organize patterns of coactivity among individual neurons during learning and memory recall.
🧠Together, these findings reveal a mechanism linking learning, memory consolidation, and recall.
They also suggest that the two-stage model of memory extends to humans. However, the oscillation pacing wake activity is slower and less continuous in humans: ~2 Hz and occurring in brief bursts.
Brain Network Dynamics Unit
😴Those coactivity motifs are later reactivated in hippocampal ripples during post-learning rest.
The stronger this reactivation, the better memories were recalled later.
We also observed similar 2-Hz oscillations during REM sleep (just like theta oscillations in other mammals !)
🧵 How does the human brain turn experiences into memories?
During my four years of PhD at Oxford, I investigated this question through a collaboration between Oxford, Toulouse, and Paris, recording directly from the human brain during a relational memory task.
